Articles, Environmental, Food, Pharmaceutical

Scope of Analysis of Cosmetics and Hygiene Products: ALS Life Sciences São Paulo

ALS Life Sciences offers chemical and biological assays that apply to the quality control, registration and/or safety of hygiene products, children’s products, cosmetics and perfumes. We conduct microbiological testing, including challenge testing, physical-chemical studies and in vitro testing, within a solid quality system recognized by CGCRE (General Coordination of Inmetro Accreditation), ANVISA and others.

Portfolio of work

Microbiological analyses

Microbiological analyses for the quality control of products for use by children, products that come in contact with eyes or mucous membranes and other cosmetic products susceptible to microbiological contamination, according to Resolution nº 481 of 23/09/1999. For the register of hygiene products, products for use by children, cosmetics and perfumes according to Resolution nº 38 of 21/03/2001.

Counting of total aerobic mesophilic microorganisms, Pseudomonas aeroginosa, Staphylococus aureus and total coliforms and faecal coliforms, clostridios sulfite reducers, among others.

Challenge Test

The challenge test validates the efficiency of the preservative system used in formulations more susceptible to contamination.

Physical-chemical analyzes

Physical-chemical analyzes for the quality control and development of new cosmetics allow to establish and verify the technical specifications of the products.

Organoleptic characteristics (appearance and color), pH, viscosity, density, dry matter, volatile materials, among others.

Ames test

The Ames test is an “in vitro” test that enables the mutagenic potential of both new ingredients and formulations to be assessed. The interactions between the ingredients of a formulation can alter the potential risk in relation to the known risk of isolated ingredients.

Besides the set of analyses mentioned above, other physical-chemical analyses for identification and dosage of the active and ingredients of the formulation that are included in the Quality Control Guide of cosmetic products of ANVISA, 2008.

In vitro micronucleus test

The objective of the micronucleus test is to identify substances that cause possible genotoxic effects, mutagenic potential, of several products.

In vitro skin and eye irritation tests

In vitro methods are used to assess the potential for corrosion or severe eye or skin irritation of various products.

Accreditations

  • CGCRE (Coordination of Accreditation of Inmetro)
  • ANVISA

Applications

  • Resolution No. 481/1999: Establishes parameters for microbiological control of Personal Hygiene Products, Cosmetics and Perfumes.
  • Resolution nº 211/2005: Classifies Personal Hygiene Products, Cosmetics and Perfumes – revoked by rdc 04/14 and rdc 07/15.
  • Resolution 38/2001: Technical Regulation for Cosmetic Products for Child Use – revoked by rdc 15/15.
  • Ordinance No. 1,480 / 1990: Technical regulation for the control of disposable hygienic absorbent products, for external and intravaginal use – revoked by rdc 142 and 148 of 2017.

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